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In Python 2, a call to the input() function, input(prompt) is equivalent to eval(raw_input(prompt)). Evaluating user input without any checking can be a serious security flaw.
Get user input with raw_input(prompt) and then validate that input before evaluating. If the expected input is a number or string, then ast.literal_eval() can always be used safely.
Python Standard Library: input, ast.literal_eval.
Wikipedia: Data validation.
Common Weakness Enumeration: CWE-94.
Common Weakness Enumeration: CWE-95.